TABLE 2.
n-3 PUFA Diet Group | Brain Lipid | Slope, Days | SE, Days | P Value | T1/2 (days) | Jout (µmol/brain/day) | Loss/Brain/Day (%) |
---|---|---|---|---|---|---|---|
Adequate | |||||||
Total PL | −0.006830 | 0.0006142 | <0.0001 | 44 | 0.248 | 1.6 | |
ChoGpl | −0.01110 | 0.0007045 | <0.0001 | 27 | 0.103 | 2.6 | |
EtnGpl | −0.006694 | 0.0006154 | <0.0001 | 45 | 0.149 | 1.5 | |
PtdIns | −0.01137 | 0.0008117 | <0.0001 | 26 | 0.080 | 2.6 | |
PtdSer | −0.005847 | 0.0007621 | <0.0001 | 51 | 0.014 | 1.4 | |
Deprived | |||||||
Total PL | −0.006581 | 0.0005942 | <0.0001 | 46 | 0.281 | 1.5 | |
ChoGpl | −0.01067 | 0.0006158 | <0.0001 | 28 | 0.123 | 2.4 | |
EtnGpl | −0.005873 | 0.0006609 | <0.0001 | 51 | 0.149 | 1.4 | |
PtdIns | −0.01071 | 0.0007731 | <0.0001 | 28 | 0.088 | 2.5 | |
PtdSer | −0.005276 | 0.0007224 | <0.0001 | 57 | 0.015 | 1.0 |
Slopes for decline of [3H] AA radioactivity in brain phospholipids and corresponding calculated half-lives, equation 3, (T1/2) = log10 (2)/slope of regression line and rates of AA loss; equation 4, Jout (µmol/brain/day) = ln(2)CAA/T1/2. p-values designate significance of difference of slope from 0. ChoGpl and PtdIns were significantly different compared with EtnGpl and PtdSer within the same dietary group; P < 0.05. Mean ± SE brain weight; 2.02 ± 0.34 and 2.10 ± 0.52 g, n-3 PUFA adequate and deprived groups, respectively. See Table 1 for abbreviations.