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. 2010 Jan 15;24(2):447–463. doi: 10.1210/me.2009-0295

Figure 1.

Figure 1

Expression profiling of miRNAs and genes in human clear cell ovarian cancer cell lines and NOSE cultures. A, Heat map representation of miRNAs overexpressed (yellow) and underexpressed (blue) in clear cell ovarian cancer compared with NOSE (P < 0.01, fold change >2). Rows, miRNAs; columns, Profiled samples. Two candidate oncogenic miRNAs, mir-182 and mir-30a, and two candidate tumor suppressor miRNAs, mir-22 and mir-100, are labeled. B, Heat map representation of transcripts overexpressed (yellow) and underexpressed (blue) in cancer vs. normal (P < 0.01, fold change >2). Rows, Transcripts; columns, Profiled samples. C, Numbers of predicted miRNA-mRNA functional pairs for each algorithm and intersection of algorithms based on anticorrelated expression in clear cell ovarian cancer.