Table 5.

Top 25 mir-30a predicted target genes that were underexpressed in clear cell ovarian cancer and up-regulated after mir-30a knockdown

Gene	Description	Microarray fold change (clear cell vs. NOSE)	Microarray fold change (mir-30a knockdown)	Algorithm
AVEN	Apoptosis, caspase activation inhibitor	−3.01	+1.19	T
DEXI	Dexamethasone-induced transcript	−2.26	+1.18	T, P
SCAMP1	Secretory carrier membrane protein 1	−2.45	+1.17	T, M
GALNT1	UDP-N-acetyl-α-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1)	−2.42	+1.16	T, P, M
GJA1	Gap junction protein, α 1, 43 kDa	−7.59	+1.15	T, P, M
ACVR1	Activin A receptor, type I	−2.32	+1.15	T, P, M
P4HA2	Prolyl 4-hydroxylase, α polypeptide II	−5.34	+1.14	T, P, M
MARCKS	Myristoylated alanine-rich protein kinase C substrate	−7.93	+1.13	T, P
MBNL2	Muscleblind-like 2 (Drosophila)	−4.41	+1.13	T, M
DACT1	Dapper, antagonist of β-catenin, homolog 1 (Xenopus laevis)	−2.72	+1.13	T, M
EXTL2	Exostoses (multiple)-like 2	−2.48	+1.12	T, P, M
MXRA5	Matrix-remodeling associated 5	−18.47	+1.11	T
PDE5A	Phosphodiesterase 5A, cGMP-specific	−13.27	+1.11	T
ATXN1	Ataxin 1	−4.98	+1.11	T, P, M
FKBP3	FK506 binding protein 3, 25 kDa	−2.47	+1.11	T, M
SSR3	Signal sequence receptor, γ (translocon-associated protein γ)	−2.35	+1.11	T, M
DSTYK	Dual serine/threonine and tyrosine protein kinase	−2.31	+1.11	T, P
S100PBP	S100P-binding protein	−2.11	+1.11	T, M
C14orf129	Chromosome 14 open reading frame 129	−2.01	+1.11	T, M
NTNG1	Netrin G1	−6.37	+1.10	T, M
BNC1	Basonuclin 1	−3.91	+1.10	T, P, M
FRMD4A	FERM domain containing 4A	−2.47	+1.10	T
NT5E	5′-Nucleotidase, ecto (CD73)	−2.39	+1.10	T
SEC23A	Sec23 homolog A (S. cerevisiae)	−2.03	+1.10	T, P, M
CALD1	Caldesmon 1	−6.46	+1.09	T, M

The table lists only those targets that were at least predicted by TargetScan. Prediction algorithms: T, TargetScan; P, PicTar; M, miRanda.