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ERαLysM−/− mice exhibit no changes in total body or uterine weight. A, Total body weight of two cohorts of female ERαLysM−/− and ERαf/f littermate mice. No differences were observed between the two genotypes (n = 9–23 mice per group). B, Wet uterine weight of 28-wk-old female mice which were sham-operated or ovariectomized (OVX) 6 wk earlier (n =10–13 mice per group). Bars, Mean ± sd; *, P < 0.05 vs. respective sham-operated mice.
