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. 2009 Dec 16;151(2):606–616. doi: 10.1210/en.2009-1135

Figure 2.

Figure 2

Effects of central LIF on food intake in WT mice. A, Cumulative food intake after i.c.v. bolus injection of LIF (100 ng) vs. vehicle in wild-type mice. Mice fasted overnight and pretreated with ipketorolac (40 mg/kg). B, Cumulative food intake in LIF-treated mice expressed as percent reduction compared with vehicle. Inhibition of food intake was significant at 2 and 4 h posttreatment. Data are expressed as mean ± sem. Statistics calculated two-way ANOVA followed by post hoc analysis using a Bonferroni corrected t test (**, P < 0.01 vs. vehicle).