Table 4.

Differentially expressed genes in the molecularly defined ALK+ ALCL

	Genes in classifier	Other differentially expressed genes
Classical ALCL markers	ALK, CD30, MUC1
Immunoregulatory cytokines	IL26, IL31RA, IL9, IL1R2	IL20, IL22, IL2RA, IL1RAP, IL1R1
TH17-cell–associated	IL17A, IL17F, RORγ
Proliferation-related	CCNA1, AGT, PDE4DIP, UPK1B	CDC27, FGF5, FOSL2
Genes noted in other tumors	RRAD, RARα, NRCAM, TMEM158, CA12	VCAN, TNFRSF12A
STAT3 regulation targets	SERPINB3, SERPINB4	SOCS1, SOCS3
Cytotoxic molecules		PRF1, GZMB
Immunosuppressive response		LILRA3

For abbreviations, see Table 2.

^*Only representative genes are included in each signature.