Table 1.
Characteristics of the asthmatic subjects examined
| All subjects | Responders | Nonresponders | |
|---|---|---|---|
| Number | 23 | 8 | 15 |
| Age, yrs (M ± SD) | 32.6 ± 10.8 | 31.1 ± 13.2 | 33.4 ± 9.8 |
| Sex (Male/Female) | 13/10 | 6/2 | 7/8 |
| Atopy (yes/no) | 17/6 | 5/3 | 12/3 |
| Smoking habit (yes/ex/no) | 0/5/18 | 0/2/6 | 0/3/12 |
| FEV1, % predicted (M ± SD) | 96.9 ± 12.0 | 93.4 ± 15.9 | 98.8 ± 9.4 |
| PD20FEV1 meth, mg (GM) | 0.263 | 0.366 | 0.218 |
| ICS, μg/d (median, range) | 500(200-1000) | 500(250-1000) | 500(200-1000) |
FEV1:Forced expiratory volume in one second ; M ± SD: mean ± standard deviation; GM: geometric mean. PD20FEV1 meth: cumulative dose of methacoline provoking a 20% decrease in FEV1 from baseline value; ICS: Inhaled corticosteroids.