Figure 5.

Statistical significance of the relative occurrence of Sp1 binding sites within different CGI classes and GC-rich shuffled sequences. X-axis: theoretical statistical significance (P-value); Y-axis: the overall fraction of sequences having a statistical significance less or equal than that at the X-axis. A higher statistical significance value reflects more Sp1 sites scoring above the PWM threshold within the selected CGI. CGI classes and GC-rich shuffled sequences are defined in Methods.