Table 4.
12 year risk and adjusted relative risk of developing arteriovascular disease by Coxiella burnetii infection among 1647 residents of Val de Bagnes, Switzerland*
| Never infected (n=1238)
|
Acutely infected (n=409)
|
Relative risk (95% CI)† | ||||
|---|---|---|---|---|---|---|
| No of cases | Risk (%) | No of cases | Risk (%) | |||
| Arterial disease‡: | 47 | 4 | 28 | 7 | 2.2 (1.4 to 3.6) | |
| Cerebrovascular accident | 11 | 1 | 11 | 3 | 3.7 (1.6 to 8.4) | |
| Cardiac ischaemia | 33 | 3 | 17 | 4 | 1.9 (1.04 to 3.4)§ | |
| Arteriopathy | 7 | 0.6 | 1 | 0.2 | 0.4 (0.1 to 3.5) | |
| Aortic dissection | 3 | 0.2 | 2 | 0.5 | 2.3 (0.4 to 13.9) | |
*
People with serological evidence of infection with Coxiella burnetii occurring before 1983 were excluded as were those who had had an arterial disease diagnosed before 1983.
†
Adjusted for age and sex using Cox proportional hazard models.
‡
The sum of the individual arterial diagnoses is greater than the total number of participants with arterial disease because 10 people had more than one type of arteriovascular event. §P=0.04.