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. 2010 Feb 9;5(2):e9112. doi: 10.1371/journal.pone.0009112

Figure 2. SOX2 protein is highly expressed in the pathogenesis of lung SCC but not of adenocarcinoma.

Figure 2

A. Representative photomicrographs displaying the immunohistochemical expression of SOX2 protein in histological tissue sections of normal bronchial epithelia, preneoplastic lesions representing SCC development (Hyperplasia, Dysplasia and carcinoma in situ), and in well (Well SCC) and poorly (Poor SCC) differentiated SCCs. B. Representative photomicrographs of SOX2 expression in lung parenchyma (LP), atypical adenomatous hyperplasia (AAH), alveolar bronchiolization structures (AB), and in acinar adenocarcinoma and bronchioalveolar carcinoma (BAC).