Table 3.

Effect of the CETP-TaqIB polymorphism on lipid concentrations and particle size^*.

	B2 carriers (n=676)	B1/B1 (n=326)
Variable	Mean ± SE	Mean ± SE	P†
Total cholesterol, mmol/L	5.04±0.03	4.86±0.04	0.001
LDL cholesterol, mmol/L	3.22±0.02	3.09±0.04	0.005
HDL cholesterol, mmol/L	1.24±0.01	1.17±0.01	0.001
Triglycerides, mmol/L	1.26±0.01	1.26±0.01	0.942
HDL particle size, nm	8.87±0.01	8.81±0.01	0.022
LDL particle size, nm	20.84±0.03	20.65±0.51	0.003
VLDL particle size, nm	50.82±0.29	51.17±0.49	0.491
Large HDL, g/L	0.17±0.04	0.14±0.07	<0.001
Medium HDL, g/L	0.03±0.02	0.03±0.03	0.377
Small HDL, g/L	0.21±0.02	0.20±0.03	0.578
IDL, g/L	0.04±0.02	0.05±0.04	0.097
Large LDL, g/L	0.42±0.02	0.37±0.03	0.040
Small LDL, g/L	0.47±0.01	0.50±0.02	0.192
Medium small LDL, g/L	0.18±0.01	0.20±0.01	0.185
Very small LDL, g/L	0.28±0.01	0.32±0.01	0.032
Large VLDL, g/L	0.17±0.02	0.16±0.03	0.493
Medium VLDL, g/L	0.34±0.02	0.32±0.03	0.238
Small VLDL, g/L	0.12±0.03	0.12±0.06	0.520

^*Sample size of 996 for particle size (n=674 and 322 for B2 carriers and B1/B1, respectively). Values are mean ± SE.

^†P values were adjusted for age, gender, BMI, field center, physical activity, smoking habit, alcohol consumption, CHD, prior medications, hormone treatment, and family relationships.