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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Clin Immunol. 2009 May 23;134(2):104. doi: 10.1016/j.clim.2009.04.014

Figure 1. Immune regulation by Fc receptors of granuloma formation in Wegner's granulomatosis.

Figure 1

This cartoon depicts some of the cytokines and immune cells involved in granuloma formation. The neutrophil is a central player in WG pathogenesis and is activated and/or inhibited by ANCA signals through the FcRs.