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. Author manuscript; available in PMC: 2010 Feb 9.
Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 5;144B(8):1054. doi: 10.1002/ajmg.b.30549

Figure 1. Interactions of Genetic Variation at a Particular Locus (GV) and Depression (Dep) on Risk of Psychotic Symptoms in Alzheimer Disease (AD+P).

Figure 1

Correlations are shown as bold arrows, dashed arrows are correlations that weaken or disappear after consideration of the other risk factor. A. GV and Dep are independent risk factors for AD+P. B. GV yields both AD+P and Dep, i.e. Dep is a proxy for GV as a risk factor for AD+P. C. Dep mediates the effect of GV on AD+P risk. D. GV moderates the effect of Dep on AD+P risk.