. Author manuscript; available in PMC: 2010 Feb 9.

Published in final edited form as: Am J Med Genet B Neuropsychiatr Genet. 2007 Dec 5;144B(8):1054. doi: 10.1002/ajmg.b.30549

Table 5.

Cox Proportional Hazard Model for Risk of Psychosis Including Genotype, Depression Score, Medications, and Genotype^*Depression Interaction Term

Variable	Parameter Estimate	(S.E.)^*	Hazard Ratio	χ²^#, p
TT vs TC/CC	0.444	0.33	1.56	1.85, 0.17
Age^**	0.015	0.05	1.01	0.10, 0.75
Education	0.076	0.04	1.08	3.90, 0.05
MMSE^**	−0.102	0.02	0.90	38.3, <.0001
Onset Age	−0.008	0.05	0.99	0.03, 0.86
Gender	−0.223	0.22	0.80	1.04, 0.31
Depression Severity^**	0.101	0.02	1.11	24.0, <.0001
Cognitive Enhancers^**	0.284	0.24	1.33	1.36, 0.24
Antipsychotics^**	−0.440	0.51	0.64	0.75, 0.38
Antidepressants^**	0.622	0.21	1.86	8.78, 0.003
Sedative/Hypnotics^**	0.189	0.29	1.21	0.41, 0.52
Genotype^*Depression Severity	−0.048	0.02	0.95	4.35, 0.037

S.E.=Standard Error

^**

Time Dependent Covariates

Wald X² with 1 df