Fig. 2.
Sub-lethal damage repair assay showing the compromised repair capacity of SCC-25 cells due to treatment with SAHA. SCC-25 cells were pre-treated with either 0.0 μM (●) or 0.5 μM (■) for 24 h and then two doses of 2 Gy each were delivered either simultaneously or at increasing times apart. SCC-25 cells showed decreased repair capacity when the interval between two radiation doses was more than 60 min. Each point on the survival curve represents the surviving fraction ± SE from three separate experiments.