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Summary of MLL aberrations
| SAHA Treatment |
Total aberrations |
DNA rearrangements |
Translocation (%) |
Microhomology (bp) |
|---|---|---|---|---|
| 0.0 μM | 14 | 4 | 28.57 | 4.5 ± 1.3 |
| 0.5 μM | 12 | 5 | 41.67 | 4.6 ±2.1 |
| 2.0 μM | 15 | 9 | 60.00 | 3.1 ± 0.8 |
All the three groups were treated with anti-CD95 antibody following pre-treatment with 0.0 μM (DMSO only), 0.5 μM and 2.0 μM SAHA respectively.
