Table 1.
Distribution of antimicrobial resistance genes among the Enterobacteriaceae clinical isolates
No. (%) of strains positive for the genes |
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β-lactamase resistance genes |
quinolone and aminoglycoside resistance genes |
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AmpC |
16S rRNA methylase |
qepA | Qnr |
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Species | No. of strains | blaCTX-M-1 groupa | blaCTX-M-2 group | blaCTX-M-9 groupb | blaSHVc | blaTEM | blaCMY-1 | blaCMY-2 | blaDHA | blaACC | blaACT | blaFOX | aac(6′)-Ib-cr | armA | rmtB | rmtC | qnrA | qnrB | qnrC | qnrS | |
E. coli | 15 | 12 | 0 | 3 | 1 | 13 | 0 | 0 | 2 | 0 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 2 |
K. pneumoniae | 15 | 14 | 0 | 0 | 13 | 14 | 0 | 0 | 2 | 0 | 0 | 0 | 9 | 3 | 0 | 0 | 0 | 0 | 5 | 0 | 9 |
E. cloacae | 5 | 4 | 0 | 0 | 4 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 2 | 0 | 4 |
C. freundii | 3 | 3 | 0 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 0 |
P. mirabilis | 1 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 1 |
Total | 39 | 34 (87) | 0 (0) | 3 (8) | 19 (49) | 35 (90) | 0 (0) | 0 (0) | 4 (10) | 0 (0) | 0 (0) | 0 (0) | 18 (46) | 5 (13) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 12 (31) | 0 (0) | 16d (41) |
aTwenty-four isolates with blaCTX-M-15, six isolates with blaCTX-M-3 and four isolates with blaCTX-M-55.
bTwo isolates with blaCTX-M-14 and one isolate with blaCTX-M-24.
cSix isolates with blaSHV-12, one isolate each with blaSHV-28, blaSHV-32 and blaSHV-11, respectively, and 10 isolates with blaSHV-1.
dFour isolates also positive for qnrB.