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. Author manuscript; available in PMC: 2010 Feb 9.

Published in final edited form as: Clin Exp Allergy. 2007 Sep;37(9):1392. doi: 10.1111/j.1365-2222.2007.02775.x

Airway mucus metaplasia. (A) qPCR for MUC-5AC expressed as fold increase in copy number; n=5-8 mice/group. (B) PAS grading. (C) PAS positive (deep purple) staining demonstrating mucus metaplasia in 6-week (10×), 6-month (10×), 12-month (10X), 18-month (20×) OVA-mice; none in age-matched naïve mice. One representative histologic sample per group shown. *, p<0.05; **, p<0.01; ***, p<0.001 compared to 6-week OVA-mice.

Airway mucus metaplasia. (A) qPCR for MUC-5AC expressed as fold increase in copy number; n=5-8 mice/group. (B) PAS grading. (C) PAS positive (deep purple) staining demonstrating mucus metaplasia in 6-week (10×), 6-month (10×), 12-month (10X), 18-month (20×) OVA-mice; none in age-matched naïve mice. One representative histologic sample per group shown. *, p<0.05; **, p<0.01; ***, p<0.001 compared to 6-week OVA-mice.