. Author manuscript; available in PMC: 2010 Feb 9.

Published in final edited form as: J Cell Physiol. 2008 Oct;217(1):40. doi: 10.1002/jcp.21472

Table 1.

Micro-CT analysis of femurs in 1-day, 7-day and 8-week-old wild type and Runx2 haploinsufficiency mice

Genotype	Runx2+/+ 1 day	Runx2+/− 1 day	Runx2+/+ 7 day	Runx2+/− 7day	Runx2+/+ 8w	Runx2+/− 8w
BMD (mg/cc)	9.56 ± 0.32	7.12 ± 0.29^*	11.69 ± 0.46	9.71 ± 0.23^*	24.12 ± 1.12	20.45 ± 1.23^*
BV/TV (%)	26.54 ± 1.43	18.26 ± 0.96^*	36.87 ± 1.84	23.98 ± 1.36^*	72.98 ± 3.18	58.33 ± 3.76^*
Tb.Th (μm)	45.65 ± 2.89	31.56 ± 1.59^*	78.12 ± 4.23	57.64 ± 4.56^*	189 ± 8.66	146 ± 5.6^*
Tb.N (mm⁻¹⁾	5.12 ± 0.32	4.65 ± 0.26	4.42 ± 0.46	3.12 ± 0.21	3.67 ± 0.013	1.68 ± 0.006^*
Tb.Sp (μm)	134 ± 10.51	165 ± 15.6	150 ± 8.12	183 ± 11.65	181 ± 6.12	229 ± 11.23^*

Data are mean±SEM from 5 individual mice.

Significant difference from wild–type Runx2 +/+ mice.