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. Author manuscript; available in PMC: 2010 Aug 1.
Published in final edited form as: Mod Pathol. 2009 Oct 23;23(2):169–176. doi: 10.1038/modpathol.2009.155

Figure 1.

Figure 1

a. and b. : Sessile Serrated Adenoma, H&E, Proximal Colon, 20X: a. Section of proximal colon stained with hematoxylin and eosin showing some features of sessile serrated adenoma including dilatation of the base of the crypts, crypts extending parallel to the muscularis mucosae, serration at the base of the crypts, and eosinophilic change of the surface epithelium. b. Section of proximal colon sessile serrated adenoma in Figure 1a. with MUC6 immunostaining of the basal crypts.

c. and d. : Hyperplastic Polyp, H&E, Distal Colon, 20X: c. Section of distal colon stained with hematoxylin and eosin showing features of hyperplastic polyp including serration in the upper half to one third of the crypts with normal proliferation including a proliferation zone at the base of the crypts that is symmetric, and crypts that remain narrow and lined with proliferative cells. d. Section of distal colon hyperplastic polyp in Figure 1c. with MUC6 immunostaining of the basal crypts.