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. Author manuscript; available in PMC: 2010 Dec 1.
Published in final edited form as: FEMS Immunol Med Microbiol. 2009 Aug 18;57(3):214–228. doi: 10.1111/j.1574-695X.2009.00598.x

Fig. 2.

Fig. 2

Growth promoting effects of adenosine on EPEC strains. Adenosine at various concentrations was added to minimal medium (MM) or DMEM medium and growth was measured by culture turbidity (optical density at 600 nm, Panels A–D) or bacterial protein content (Panel E) at different times. Panel A, effect of adenosine on EPEC strains E2348/69 and B171-8 in MM with 2 mM glucose as the carbon source. Panel B, effect of adenosine and N-ethylcarboxamidoadenosine (NECA) on EPEC strain E2348/69 in MM with 2 mM succinate as carbon source. Panel C, growth promotion by adenosine in DMEM. In Panels A– C concentrations of adenosine of 40 μM or greater produced statistically significant increases in growth for strains B171 and E22, and for strain E2348/69 adenosine at ≥20 μM significantly stimulated growth (p < 0.05). Panel D, time course of adenosine effects on E2348/69 growth. Panel E, comparison of growth effects of adenosine with other nucleosides. Panel F, structure of N-ethylcarboxamidoadenosine (NECA) in comparison with adenosine.