Table 4.
Gene | Max_SNP | Allele | MAF | Chr | Phy_loc | Role | p_max_snp |
---|---|---|---|---|---|---|---|
PAK1 | rs2105803 | A/G | 0.21 | 11q14.1 | 76911659 | Upstream | 0.001 |
FAK1 | rs11167023 | A/G | 0.18 | 8q24.3 | 142175410 | Upstream | 0.002 |
EphA7 | rs6941459 | C/T | 0.44 | 6q16.1 | 94593345 | Upstream | 0.003 |
PIK3CG | rs10953518 | A/G | 0.14 | 7q22.3 | 106187118 | Upstream | 0.006 |
PAK7 | rs742452 | C/G | 0.23 | 20p12.2 | 9684363 | Intron | 0.009 |
RASA1 | rs3827607 | A/G | 0.42 | 5q14.3 | 86712976 | Intron | 0.010 |
FYN | rs2182644 | A/G | 0.09 | 6q21 | 112245575 | Intron | 0.012 |
RAC1 | rs836472 | C/T | 0.25 | 7p22.1 | 6401429 | Intron | 0.013 |
EFNA5 | rs17159152 | C/T | 0.27 | 5q21.3 | 106206807 | Downstream | 0.017 |
CDC42 | rs17837965 | A/G | 0.05 | 1p36.12 | 22267212 | Intron | 0.017 |
PTPN11 | rs7132204 | A/G | 0.39 | 12q24.13 | 111688424 | Downstream | 0.018 |
EphA3 | rs6797260 | A/T | 0.32 | 3p11.2 | 89385176 | Intron | 0.021 |
EphA1 | rs7800937 | A/G | 0.08 | 7q35 | 142803429 | Intron | 0.028 |
EphA5 | rs1514271 | C/G | 0.34 | 4q13.1 | 65799362 | Downstream | 0.028 |
EphA4 | rs17349283 | A/G | 0.46 | 2q36.1 | 221798041 | Downstream | 0.037 |
LIMK2 | rs2267171 | C/T | 0.07 | 22q12.2 | 29979632 | Intron | 0.038 |
ROCK2 | rs6716817 | A/G | 0.47 | 2p25.1 | 11303285 | Intron | 0.039 |
ADAM10 | rs4775085 | A/G | 0.06 | 15q22.1 | 56737283 | Intron | 0.040 |
CFL1 | rs3903072 | A/C | 0.48 | 11q13.1 | 65339642 | Downstream | 0.042 |
ACTG2 | rs1721241 | C/G | 0.22 | 2p13.1 | 73981899 | Intron | 0.043 |
EphA8 | rs12128121 | A/G | 0.10 | 1p36.12 | 22804749 | Downstream | 0.044 |
ACTB | rs1474445 | C/T | 0.18 | 7p22.1 | 5563375 | Upstream | - |
NGEF | rs895432 | C/T | 0.05 | 2q37.1 | 233465941 | Coding exon | - |
FAK2 | rs2251430 | A/G | 0.14 | 8p21.2 | 27364766 | Intron | - |
PAK2 | rs843530 | C/T | 0.46 | 3q29 | 197965421 | Intron | - |
ACTA2 | rs1937330 | A/T | 0.08 | 10q23.31 | 90844025 | Upstream | - |
PAK6 | rs8035733 | A/G | 0.18 | 15q15.1 | 38330232 | Intron | - |
PAK4 | rs513053 | A/G | 0.38 | 19q13.2 | 44332986 | Intron | - |
CFL2 | rs17453240 | C/G | 0.09 | 14q13.2 | 34248919 | 3′ near gene | - |
ACTG1 | rs9907460 | G/T | 0.38 | 17q25.3 | 77066757 | Downstream | - |
LIMK1 | rs2855726 | A/G | 0.33 | 7q11.23 | 73155050 | Intron | - |
EphA2 | rs904107 | A/G | 0.05 | 1p36.13 | 16361410 | Promoter | - |
ROCK1 | rs1552110 | A/G | 0.05 | 18q11.1 | 16924725 | Intron | - |
EFNA3 | rs7368345 | A/G | 0.50 | 1q22 | 153346714 | Downstream | - |
ACTA1 | rs499689 | C/T | 0.40 | 1q42.13 | 227632355 | Downstream | - |
Note: “Max_SNP”: the most significant SNP; “MAF”: minor allele frequency in our sample; “Chr”: chromosome; “Phy_loc”: physical location; “-” denotes that p value > 0.05.