Table 1.
Genotype | Spontaneous heteroallelic recombination |
||
---|---|---|---|
Rate χ 10−7 |
Fold changeb | ||
RAD52 | rad52-Y66A | ||
wild type | 10 ± 1.3** | 82 ± 7.1*,** | 8.2 |
rad52Δ | 0.1 ± 0.05* | nac | na |
mre11Δ | 79 ± 11*,** | 60 ± 8.1*,** | 0.8 |
rad51Δ | 0.3 ± 0.07* | 0.4 ± 0.1*,** | 1.3 |
mre11Δ rad51Δ | 0.4 ± 0.08* | ndd | na |
ctf4Δ | 75 ± 10*,** | 100 ± 15*,** | 1.3 |
msh2Δ | 20 ± 2.1*,** | 238 ± 40*,** | 12 |
rad52Δ msh2Δ | 0.2 ± 0.1* | na | na |
mre11Δ msh2Δ | 240 ± 32*,** | 418 ± 53*,** | 1.7 |
P < 0.05 compared to the wild type.
P < 0.05 compared to the rad52Δ.
Recombination rate (events per cell per generation) is presented as the mean ± SD as described in Materials and Methods.
Fold change for the rad52-Y66A allele compared to RAD52.
Not applicable.
Not determined.