Skip to main content
. Author manuscript; available in PMC: 2011 Jan 2.
Published in final edited form as: DNA Repair (Amst). 2009 Nov 4;9(1):23. doi: 10.1016/j.dnarep.2009.10.001

Table 1.

Spontaneous mitotic recombination between chromosome-chromosome (C x C) heteroalleles.

Genotype Spontaneous heteroallelic recombination
Rate χ 10−7
Fold changeb
RAD52 rad52-Y66A
wild type 10 ± 1.3** 82 ± 7.1*,** 8.2
rad52Δ 0.1 ± 0.05* nac na
mre11Δ 79 ± 11*,** 60 ± 8.1*,** 0.8
rad51Δ 0.3 ± 0.07* 0.4 ± 0.1*,** 1.3
mre11Δ rad51Δ 0.4 ± 0.08* ndd na
ctf4Δ 75 ± 10*,** 100 ± 15*,** 1.3
msh2Δ 20 ± 2.1*,** 238 ± 40*,** 12
rad52Δ msh2Δ 0.2 ± 0.1* na na
mre11Δ msh2Δ 240 ± 32*,** 418 ± 53*,** 1.7
*

P < 0.05 compared to the wild type.

**

P < 0.05 compared to the rad52Δ.

a

Recombination rate (events per cell per generation) is presented as the mean ± SD as described in Materials and Methods.

b

Fold change for the rad52-Y66A allele compared to RAD52.

c

Not applicable.

d

Not determined.