Table 2.
Genotype | Spontaneous heteroallelic recombination |
||
---|---|---|---|
Rate × 10−7 |
Fold changeb | ||
RAD52 | rad52-Y66A | ||
wild type | 0.9 ± 0.2** | 2.1 ± 0.3** | 2.3 |
rad52Δ | 0.04 ± 0.02* | nac | na |
mre11Δ | 2.2 ± 0.6** | 0.5 ± 0.1** | 0.2 |
rad51Δ | 0.3 ± 0.1* | 0.2 ± 0.06* | 0.7 |
mre11Δ rad51Δ | 0.2 ± 0.05◆ | ndd | na |
ctf4Δ | 8.1 ± 2.1*,** | 3.5 ± 1.3*,** | 0.4 |
msh2Δ | 1.4 ± 0.2** | 0.7 ± 0.1** | 0.5 |
P < 0.05 compared to the wild type.
P < 0.05 compared to the rad52A.
P = 0.05 compared to the wild type.
Recombination rate (events per cell per generation) is presented as the mean ± SD as described in Materials and Methods.
Fold change of the rad52-Y66A allele compared to the RAD52 on the different genetic backgrounds.
Not applicable.
Not determined.