Skip to main content
. Author manuscript; available in PMC: 2011 Jan 2.
Published in final edited form as: DNA Repair (Amst). 2009 Nov 4;9(1):23. doi: 10.1016/j.dnarep.2009.10.001

Table 2.

Spontaneous mitotic recombination between chromosome-plasmid (C × P) heteroalleles in haploid strains

Genotype Spontaneous heteroallelic recombination
Rate × 10−7
Fold changeb
RAD52 rad52-Y66A
wild type 0.9 ± 0.2** 2.1 ± 0.3** 2.3
rad52Δ 0.04 ± 0.02* nac na
mre11Δ 2.2 ± 0.6** 0.5 ± 0.1** 0.2
rad51Δ 0.3 ± 0.1* 0.2 ± 0.06* 0.7
mre11Δ rad51Δ 0.2 ± 0.05 ndd na
ctf4Δ 8.1 ± 2.1*,** 3.5 ± 1.3*,** 0.4
msh2Δ 1.4 ± 0.2** 0.7 ± 0.1** 0.5
*

P < 0.05 compared to the wild type.

**

P < 0.05 compared to the rad52A.

P = 0.05 compared to the wild type.

a

Recombination rate (events per cell per generation) is presented as the mean ± SD as described in Materials and Methods.

b

Fold change of the rad52-Y66A allele compared to the RAD52 on the different genetic backgrounds.

c

Not applicable.

d

Not determined.