Table 3.
Spontaneous interchromosomal recombination between ade2 heteroalleles where the polymorphisms are separated by different lengths.
| Genotype | Spontaneous heteroallelic recombinationa |
|||||
|---|---|---|---|---|---|---|
| Rate × 10−7 | ||||||
| 200 bp | Fold changeb | 950 bp | Fold changeb | 1150 bp | Fold changeb | |
| wild type | 1.1±0.3 | na | 10±1.3 | na | 4.3±0.7 | na |
| rad52-Y66A | 11±1.8 | 10 | 82±7.1 | 8 | 60±7.7 | 14 |
| msh2Δ | 3.5±0.6 | 3 | 20±2.1 | 2 | 15±2.1 | 3 |
| rad52-Y66A msh2Δ | 34±4.7 | 31 | 238±40 | 24 | 342±50 | 80 |
Top: Assays for spontaneous interchromosomal recombination between ade2 heteroalleles where the polymorphisms are separated by different lengths. Dashed lines indicate the approximate number of base pairs separating each polymorphism.
a
Recombination rate (events per cell per generation) is presented as the mean ± SD as described in Materials and Methods.
b
Fold change compared to wild type.