Table 1. Genes in the GenMAPP Cell Cycle pathway significantly increased or decreased in 6 hours following treatment of PC-3 cells with luteolin.
AffyID | Gene Title | Gene Symbol |
Entrez Gene |
Fold Change |
Adjusted P Value |
---|---|---|---|---|---|
202123_s_at | v-abl Abelson murine leukemia viral oncogene homolog 1 | ABL1 | 25 | −1.71 | 0.0005804 |
204244_s_at | activator of S phase kinase | ASK | 10926 | −2.24 | 0.0000095 |
203755_at | BUB1 budding uninhibited by benzimidazoles 1 homolog beta (yeast) | BUB1B | 701 | −1.64 | 0.0004463 |
201456_s_at | BUB3 budding uninhibited by benzimidazoles 3 homolog (yeast) | BUB3 | 9184 | −1.38 | 0.0031299 |
213226_at | Cyclin A2 | CCNA2 | 890 | −2.06 | 0.0000037 |
213523_at | cyclin E1 | CCNE1 | 898 | −1.48 | 0.0010471 |
205034_at | cyclin E2 | CCNE2 | 9134 | −5.52 | 0.0000013 |
203213_at | Cell division cycle 2, G1 to S and G2 to M | CDC2 | 983 | −1.47 | 0.0012987 |
204696_s_at | cell division cycle 25A | CDC25A | 993 | −1.42 | 0.0000672 |
203967_at | CDC6 cell division cycle 6 homolog (S. cerevisiae) | CDC6 | 990 | −1.75 | 0.0000692 |
209112_at | cyclin-dependent kinase inhibitor 1B (p27, Kip1) | CDKN1B | 1027 | 2.20 | 0.0000107 |
205394_at | CHK1 checkpoint homolog (S. pombe) | CHEK1 | 1111 | −1.69 | 0.0001134 |
204817_at | extra spindle poles like 1 (S. cerevisiae) | ESPL1 | 9700 | −1.43 | 0.0008915 |
226191_at | Glycogen synthase kinase 3 beta | GSK3B | 2932 | −2.07 | 0.0000330 |
222037_at | MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) | MCM4 | 4173 | −1.62 | 0.0006883 |
205085_at | origin recognition complex, subunit 1-like (yeast) | ORC1L | 4998 | −1.50 | 0.0000122 |
204853_at | origin recognition complex, subunit 2-like (yeast) | ORC2L | 4999 | −1.53 | 0.0001676 |
211212_s_at | origin recognition complex, subunit 5-like (yeast) | ORC5L | 5001 | −2.01 | 0.0000576 |
201202_at | proliferating cell nuclear antigen | PCNA | 5111 | −1.82 | 0.0008122 |
202240_at | polo-like kinase 1 (Drosophila) | PLK1 | 5347 | −1.80 | 0.0000329 |
210567_s_at | S-phase kinase-associated protein 2 (p45) | SKP2 | 6502 | −1.40 | 0.0026516 |
212533_at | WEE1 homolog (S. pombe) | WEE1 | 7465 | −1.67 | 0.0017875 |
222985_at | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, | YWHAG | 7532 | −1.41 | 0.0023041 |