Fig. 3.

Overexpression of hVPS41 in SH-SY5Y cells ameliorates cell death in cellular models of PD. SH-SY5Y stable cell lines were treated with rotenone for 48 hrs at indicated concentration, and cell death was measured by LDH release (Fig. 3A). SH-SY5Y stable cell lines were treated with 6-OHDA for 16 hrs at indicated concentration, and cell death was measured by LDH release (Fig. 3B.). SH-SY5Y stable cell lines were treated with staurosporine for 5 hrs at indicated concentration, and cell death was measured by LDH release (Fig. 3C). * p <0.05, ** p <0.01, Student's t-test. Mean ± SEM, n=5, ANOVA test from SigmaStat.