Table 1. Behavioral spontaneous seizure count in post-SE rats.

Numbers indicate cumulative number of behavioral seizures for individual animals over 2 two-week periods: before and during IL1-ra and saline treatments (or respective period in untreated rats). No differences were observed between the two periods for each of the groups (p>0.05, both Wilcoxon and Mann-Whitney tests for paired and unpaired comparisons), and across the groups (p>0.05, Kruskal-Wallis test). No differences were observed in the direction in which frequency changed (i.e. decreased, increased and remained unchanged) among any pairs of groups (p>0.05, Fisher's exact test).

Treatment group	Before treatment	During treatment	Changes in seizure count during treatment vs. before treatment
IL1-ra	3	0	Decreased- 4 Increased- 3 Unchanged-2
	2	1
	11	5
	4	0
	6	8
	33	42
	9	71
	0	0
	4	4
Saline	7	3	Decreased- 4 Increased- 5
	1	0
	4	3
	56	2
	13	14
	5	12
	0	2
	3	39
	0	7
Untreated	11	4	Decreased- 5 Increased-4
	9	0
	10	4
	4	0
	42	4
	4	61
	0	15
	0	33
	4	7