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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: J Am Soc Echocardiogr. 2009 Nov 11;23(1):79. doi: 10.1016/j.echo.2009.09.025

Figure 2.

Figure 2

Influence of microbubble-cell attachment on signal generation in an in vitro phantom. (A) Examples of VCAM-1-targeted microbubbles attaching to TNF-α-activated SVEC4-10 cells by light microscopy. Scale bar = 20 μm. (B) Relation between the percentage of VCAM-1-targeted microbubbles attached to SVEC4-10 cells and background-subtracted signal enhancement during low-MI and high-MI imaging. The slopes are not significantly different from zero (p=0.24 and p=0.46 for high and low MI, respectively) (C) Ratio of high-MI to low-MI signal enhancement according to the extent of microbubble attachment to SVEC4-10 cells.