Table 1. Participants' Characteristics (n=25).
| Measure | Mean (SD) | Correlations with imaging makers of brain Structure Spearman ρ (p value) |
|
|---|---|---|---|
| Atrophy index1 | WMH2 | ||
| Age, Yrs, | 81.67 (3.47) |
0.58 (p=0.001) |
0.61 (p <0.0001) |
|
Minimental Score, |
27.52 (1.9) | 0.04 (p=0.4) |
−0.26 (p=0.09) |
|
Pencil and Paper DSST, correct points, |
53.48 (17.12) |
−0.48 (p=0.005) |
−0.49 (p=0.004) |
|
sDSST Accuracy, % |
0.90 (0.13) |
−0.17 (p=0.02) |
−0.77 (p<0.0001) |
|
sDSST response time, msecs |
1640.56 (314.87) |
0.29 (p=0.07) |
0.62 (p<0.0001) |
| IMAGING MAKERS OF BRAIN STRUCTURE | |||
| Atrophy index1 | 0.72 (0.08) |
- | 0.16 (p=0.2) |
| WMH2 | 0.50 (0.61) |
0.16 (p=0.2) |
- |
1
Atrophy index: (Gray Matter volume/cerebrospinal fluid volume)−1
2
White Matter Hyperintensities Measure (WMH): WMH voxel count divided by sum of gray matter and white matter voxel counts.