Table 2. Spatial distribution of correlation of accuracy with brain functional MRI activation during sDSST task performance.
This table reports the spatial distribution of the association of accuracy with the mean group activation (obtained from the sDSST > control condition contrast), including the size of cluster, the maximum Z statistic for the cluster and the location of the maximum Z statistic in Talairach coordinates. The analyses were adjusted for group assignment, atrophy index and sDSST response time. The corrected alpha is the probability of a false positive detection based on the combination of individual voxel probability thresholding and minimum cluster size thresholding.
| Regions | Cluster Size |
Peak Z- Score |
Talairach Coordinate for Peak Z-Score |
|---|---|---|---|
| Regions positively correlated with accuracy during sDSST performance | |||
| Left prefrontal cortex | 968 | 3.25 | −45.54, −8.17, 30.81 |
| Right posterior parietal cortex | 451 | 2.84 | 35.64, −53.56, 55.182 |
| Regions negatively correlated with accuracy during sDSST performance | |||
| No significant voxels | |||
This cluster had its peak in the left precentral gyrus (BA 6) extended to middle and prefrontal gyri (BA 4, 9, 44), and covered postcentral gyrus (BA 40, 43) and superior temporal gyrus (BA 42).
This cluster had its peak in the right superior parietal lobule medially (BA 7) and extended to the inferior parietal lobule (BA 40).