Table 4. Spatial distribution of functional brain MRI activation showing significant interaction of WMH burden by accuracy during sDSST task.
This table reports the regions that showed interaction of WMH volume by accuracy during the sDSST task, including the size of cluster, the maximum Z statistic for the cluster and the location of the maximum Z statistic in Talairach coordinates. Analyses were adjusted for group assignment, atrophy index and sDSST response time. The corrected alpha is the probability of a false positive detection based on the combination of individual voxel probability thresholding and minimum cluster size thresholding.
| Regions | Cluster Size |
Peak Z- Score |
Talairach Coordinate for Peak Z-Score |
|---|---|---|---|
| Regions with positive interaction term (Accuracy by WMH) | |||
| Left posterior parietal cortex | 777 | 3.08 | −37.62, −27.96, 62.191 |
| Regions with negative interaction term (Accuracy by WMH) | |||
| No significant voxels | |||
This cluster had its peak in the left postcentral gyrus (BA 3), it covered the inferior parietal lobule (BA 40) and sensori-motor cortex (pre-post-central gyri : BA 2, 3 and 4).