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. Author manuscript; available in PMC: 2010 Feb 9.
Published in final edited form as: Hum Mol Genet. 2003 Nov 12;13(1):103. doi: 10.1093/hmg/ddh004

Figure 3.

Figure 3

Strategy for amplification of t(1;22) junction fragments. The 1p22 breakpoint was localized between STS-A and STS-B markers by PCR mapping of somatic cell hybrid DNA. Repetitive elements present in this 6.7 kb breakpoint region of 1p22 are depicted. Chromosomes 1 and 22 are shown as white and shaded bars, respectively. AT-rich repeats are shown as hatched bars on both 1p22 and at the common breakpoint region of the 22q11.21 LCR-B. Sequence-specific nested primers used for junction fragment amplification are shown as arrows.