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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Retina. 2010 Jan;30(1):42. doi: 10.1097/IAE.0b013e3181bfbdb2

Figure 2.

Figure 2

Fundus photograph of the posterior pole of a HIV-positive patient with macular CMV retinitis (A) and corresponding FAF image (B) shows hypoautofluorescence with surrounding halo of hyperautofluorescence (asterisk), which corresponded to hemorrhage, retinal infiltration and retinal edema. A stippled area of hyper- and hypoautofluorescence is observed superonasal to the fovea (yellow arrow) in a smaller, non-contiguous area of active CMV retinitis. Two weeks following intravitreal foscarnet and ganciclovir, the area of active CMV retinitis has decreased (C) and the FAF image shows that the region of hypoautofluorescence has changed to an area with both hyper- and hypoautofluorescent signal (D, asterisk). Interestingly, widespread hyperautofluorescent stippling is seen on FAF imaging, which was not apparent clinically (D). At 6 months follow-up after ganciclovir implantation, the CMV retinitis has resolved (E), however, diffuse and persistent FAF abnormalities are seen, possible related to medication toxicity (F).