Figure 2.
DCAd.Neu+Ad.mIL-15+Ad.mIL-15Rα vaccination of BALB-neuT mice significantly delayed or prevented the onset of mammary tumors. Groups (n =10) of 12-week-old female BALB-neuT mice received four weekly subcutaneous injections of 1 × 106 DCAd.Neu, DCAd.Neu+Ad.mIL-15, DCAd.Neu+Ad.mIL-15Rα, DCAd.Neu+Ad.mIL-15+Ad.mIL-15Rα, DCAd.mIL-15+Ad.mIL-15Rα or DCAd.null. Mice were examined twice weekly for the formation of mammary tumors.