Table 2.
List of Exclusion Criteria
| Exclusion Criteria | Rationale |
|---|---|
| The following Axis I disorders: | These disorders require treatments not provided within the context of the CAMS trial |
| • Major Depressive Disorder | |
| • Bipolar Disorder | |
| • Psychotic Disorder | |
| • Pervasive Developmental Disorder | |
| • Uncontrolled ADHD (combined or primarily hyperactive type) | |
| • Eating Disorders | |
| • Substance Use Disorders | |
| Any Axis I disorder (excluding those mentioned above), with an ADIS CSR ≥ to the CSR of the disorders of interest (SAD, GAD, SoP) | Disorders of interest (SAD, SoP, GAD) must be the most severe and disabling conditions affecting the child |
| School refusal behavior characterized by missing > 25% of school days in most recent term | May require additional or different treatments |
| Suicidal or homicidal | Unethical to randomize to PBO |
| Two previous failed trials of an SSRI or a failed trial of an adequate course of CBT for the disorders of interest | Not likely to respond to study treatments; may require additional treatments |
| Intolerance to sertraline | Risk of side effects/adverse events |
| Confounding medical condition | Potential medical risk or confounding issue |
| Pregnancy | Potential risk of medication effects to fetus |
| Child or adolescent does not speak English | Cannot complete study assessments and CBT |