Table 4.
Baseline values | Delta values (value at end of study minus baseline) | |||||
---|---|---|---|---|---|---|
DD group | DP group | PP group | DD group | DP group | PP group | |
N | 110 | 97 | 105 | |||
Males (%) | 40.0 | 40.2 | 39.0 | |||
Age (years) | 47.3 ± 11.1 | 47.7 ± 11.6 | 50.8 ± 10.7 | |||
BMI (kg/m2) | 34.4 ± 3.9 | 33.7 ± 3.5* | 35.2 ± 3.9 | 0.01 ± 1.33 | 0.13 ± 1.10 | 0.09 ± 1.35 |
Smokers (%) | 20.9 | 20.6 | 17.1 | |||
BMD L2-L4 (g/cm2) | 1.270 ± 0.155 | 1.235 ± 0.161 | 1.251 ± 0.170 | 0.008 ± 0.036 | 0.008 ± 0.039 | 0.007 ± 0.042 |
BMD total hip (g/cm2) | 1.107 ± 0.133 | 1.067 ± 0.128 | 1.092 ± 0.130 | 0.008 ± 0.014 | 0.011 ± 0.014 | 0.009 ± 0.017 |
OPG (pg/ml) | 1875 ± 509 | 1961 ± 600 | 2092 ± 650 | 56 ± 3061 | - 34 ± 4722 | |
RANKL (pg/ml) | 0.09 ± 0.15 | 0.10 ± 0.27 | 0.05 ± 0.10 | - 0.01 ± 0.101 | 0.00 ± 0.062 | |
Serum 25(OH)D (nmol/L) | 61.3 ± 20.7 | 58.3 ± 21.2 | 60.1 ± 22.3 | 79.9 ± 31.3† | 41.7 ± 22.8† | - 2.2 ± 16.8 |
Serum PTH (pmol/L) | 5.1 ± 1.6 | 5.4 ± 1.8 | 5.7 ± 1.7 | - 0.9 ± 1.5† | - 0.7 ± 1.4* | - 0.2 ± 1.6 |
Serum calcium (mmol/L) | 2.30 ± 0.11 | 2.32 ± 0.11 | 2.31 ± 0.10 | - 0.01 ± 0.12 | - 0.02 ± 0.12 | - 0.01 ± 0.11 |
*P < 0.05; †P < 0.001 versus delta values in the PP grooup
1N = 76; 2N = 81