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Population estimated concentration-time curves (denoted by solid lines) and observed values (open circles) for plasma amifostine (Panel A); plasma WR1065 (Panel B); whole blood amifostine (Panel C); and whole blood WR1065 (Panel D). Observed amifostine and WR1065 concentrations below the LLQ were substituted with 0.125 (1/2*LLQ).
Abbreviation; LLQ, lower limit of quantitation
