Table 5.
Multivariate analysis of factors and Foxp3+ TIL associated with survival
| Variables | OS (n = 106) | PFS (n = 106) | ||||
|---|---|---|---|---|---|---|
| Hazard Ratio | 95% CI | P | Hazard Ratio | 95% CI | P | |
| Tumor (T) stage (4+3/2+1) | 0.803 | 0.331-1.949 | 0.627 | 0.930 | 0.408-2.119 | 0.863 |
| Nodal (N) status (3+2+1/0) | 5.181 | 0.679-40.071 | 0.115 | 3.880 | 0.886-16.994 | 0.072 |
| TNM stage (III+IVa+IVb/I+II) | 2.582 | 0.798-8.351 | 0.113 | 1.704 | 0.622-4.674 | 0.300 |
| Foxp3+ TILs (high/low) | 0.378 | 0.170-0.841 | 0.017* | 0.331 | 0.161-0.682 | 0.003* |
NOTE: The Cox proportional hazards regression model was used in univariate analysis.