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. 2010 Jan 13;9:6. doi: 10.1186/1476-4598-9-6

Figure 1.

Figure 1

Forskolin significantly suppresses TNF-α-induced necrotic cell death in L929 fibroblastoma cells. L929 cells were pretreated with or without forskolin (FSK, 10 μM, 30 min) and then stimulated with 10 ng/ml TNF-α for 24 h or left untreated. Cell death was measured by Annexin-V/PI double staining. The percentages of cell death are shown in the lower panel as mean ± SD; n = 3. Upper panel is representative of three independent experiments. **p < 0.01.