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Plasma (a) and brain tissue (b) AngII levels. The plasma AngII concentration increased after 14 days AngII infusion. However, there was no effect on brain AngII levels. Candesartan treatment decreased brain AngII in the basal ganglia compared with both vehicle- and AngII-infused rats. *P<0.01 vs. vehicle; †P<0.01 vs. AngII.
