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. 2010 Feb 10;5(2):e9139. doi: 10.1371/journal.pone.0009139

Table 1. Efficacy of DV-STM-07 vaccine in pregnant mice.

Strain used No of mice Death of mother Mice Aborted/resorption No of Pups Delivered by surviving mothers No of pups dead (0-10 Days)/Total no of pups No of pups dead (10-20 Days)/Total no of pups
WT Salmonella 6 1 3 15 3/15 6/12 ( p-value = 0.004)
DV-STM-07 6 0 1 12 3/12 0/9
PBS 5 0 0 27 7/27 0/20

Pregnant BALB/c mice were infected with WT and Vaccine strain DV-STM-07 (107 cfu) and were observed for abortion and the offspring outcome. With WT infection, abortion and the death of pups after delivery was more than DV-STM-07 infected mice. The data shows the representative of three independent experiments performed. Fisher's exact test was used to analyze the data. p-values are provided for statistically significant data.