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. 2010 Feb 10;5(2):e9139. doi: 10.1371/journal.pone.0009139

Table 3. Transmission profile of bacteria during pregnancy in control and vaccinated mice.

Vaccination BALB/c Pregnant (3) CFU in Mothers Blood (X102/ml) CFU in Pups taken out by caesarian(pooled data) (X102/gm wt of pup) Growth in LB from Vaginal swab of pregnant mother CFU in amniotic Fluid (X102/ml)
WT A 6 17.8 + 58
B 0 0 0 0
C 92 Dead + ND
DV-STM-07 A 0 0 0 0
B 0 0 0 0
C 0 0 0 0

Undelivered pups were dissected aseptically from WT and DV-STM-07 strain infected mice and homogenized after three days of infection. Homogenate was plated on LB agar plate and analyzed for CFU growth. There was no trans-placental transfer of Salmonella both in case of vaccine and WT infected mice. But WT mothers were positive for Salmonella in blood culture and vaginal swab culture (2 mouse) Experiment was done thrice to reproduce the results. (+; Positive, ND; Not determined).