Skip to main content
. Author manuscript; available in PMC: 2011 Feb 5.
Published in final edited form as: Circ Res. 2009 Dec 3;106(2):354. doi: 10.1161/CIRCRESAHA.109.207423

Figure 3. PLN ablation in CaMKIIδc TG mice exaggerates the phenotype of dilated cardiomyopathy.

Figure 3

A, Heart weight/body weight (HW/BW) ratio at 8 wks. B and C, Averaged echocardiographic parameters at different ages. Data are presented for B, left ventricular end-diastolic diameter (LVEDD), and for C, calculated percent fractional shortening (FS). n=4 to 6 mice per group at each age; *P<0.05 vs. WT. # P<0.05 vs. CaMKII-TG. D, Survival curves for CaMKII-TG and PLN-KO/CaMKII-TG mice. PLN ablation accentuates premature death in CaMKIIδC TG mice. Numbers of mice were as follows: CaMKII-TG, n=16; KO/TG, n=22. P <0.01 KO/TG vs. CaMKII-TG.