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. 2010 Feb 10;5(2):e9152. doi: 10.1371/journal.pone.0009152

Figure 2. Combined deficiency of Gab2 with heterozygous STAT5 leads to declines in adult HSC activity.

Figure 2

A. BM cells from 3–5 donor mice were collected and mixed 1:1 with wild-type competitor (CD45.1) and transplanted into lethally-irradiated hosts for competitive repopulation analysis. Recipient mice were bled 12 weeks later for flow cytometry analysis. Shown is the average of two independent experiments with 5 mice per group in each experiment. B. At 16 weeks post transplant, mice were bled again for multilineage analysis for the same two independent experiments. Peripheral blood leukocytes were stained with antibodies to multiple lineage markers including Gr-1, B220, Ter119, and CD4.