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. Author manuscript; available in PMC: 2011 Feb 1.
Published in final edited form as: Bioorg Med Chem Lett. 2010 Jan 4;20(3):841. doi: 10.1016/j.bmcl.2009.12.097

Scheme 1.

Scheme 1

Introduction of furano moiety. (a) propyne, Pd(PPh3)4, CuI, NEt3, DMF, rt, 22 h, 60%; (b) CuI, NEt3, MeOH, reflux, 28–45%.