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. 2009 Dec 16;107(2):633–638. doi: 10.1073/pnas.0909191107

Table 1.

Structures, IC50, Ki,app, 50% inhibition values for small-molecule inhibitors

Small-molecule inhibitor (structure and name)
 ExoI
 Arg327Ala ExoI
 RecQ
 PriA
IC50, μM 50% inhibition, μM Ki,app, μM IC50, μM (fold change) IC50, μM IC50, μM
graphic file with name pnas.0909191107fig4.jpg 8 ± 1 34 ± 9 26 ± 4 12 ± 1 (1.5) > 200 ∼200
graphic file with name pnas.0909191107fig5.jpg 23 ± 3 74 ± 34 32 ± 4 72 ± 11 (3.1) > 200 > 200
graphic file with name pnas.0909191107fig6.jpg 28 ± 6 290 ± 170 126 ± 19 41 ± 3 (1.5) ∼100 ∼60
graphic file with name pnas.0909191107fig7.jpg ∼80 310 ± 140 163 ± 33 85 ± 11 (1.1) ∼100 ∼100