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. Author manuscript; available in PMC: 2011 Feb 3.
Published in final edited form as: J Am Chem Soc. 2010 Feb 3;132(4):1359. doi: 10.1021/ja908562q

Figure 4.

Figure 4

Effect of replacement of a hydroxyl group by an amino group in selected TTR kinetic stabilizers. Percent fibril formation (% F.F.) values (black font), plasma TTR binding stoichiometry (blue font), T3 displacement from thyroid hormone receptor (red font) as well as individual efficacy scores (green font) are shown, precisely as defined in Figure 2, with the exception that average efficacy scores are not shown.