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. Author manuscript; available in PMC: 2010 Feb 10.
Published in final edited form as: Immunity. 2008 Sep 19;29(3):325. doi: 10.1016/j.immuni.2008.08.006

Fig. 2.

Fig. 2

Hematogenous DC routes. This schematic outline illustrates various routes that DCs can take to and from the blood into various lymphoid and non-lymphoid tissues. DC precursors are released from the BM and enter the blood pool, which consists of: conventional DCs (or cDC), pDCs, and DC precursors (encompassing monocytes, HSPCs, and other committed DC precursors). Potential destinations of blood-borne DCs as well as the major trafficking molecules implicated in their migration are highlighted, including (from left to right) the skin, LN, thymus, and spleen, as well as their re-entry into the BM.