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. Author manuscript; available in PMC: 2011 Jan 1.
Published in final edited form as: Radiat Res. 2010 Jan;173(1):10–20. doi: 10.1667/RR1911.1

FIG. 3.

FIG. 3

Panel A: Micro-CT coronal and axial sections through the mid-thorax of control and irradiated mice at 16 weeks after whole-thorax irradiation (137Cs γ rays) to show regional increase in lung parenchyma density (arrows) associated with pneumonitis in treated CBA/J and C57L/J mice but not C57BL/6 mice. Panel B: Micro-CT sections of a control C57L/J mouse and a C57L/J mouse at 28 weeks after 10 Gy whole-thorax irradiation with focal radio-opaque lesions (arrows) indicative of fibrosis. Panel C: Micro-CT images with three-dimensional reconstructions together with coronal and axial T2-weighted MRI of C57BL/6J mice at 28–30 weeks after whole-thorax irradiation showing increased lung density and decreased lung volume associated with the presence of pleural effusions. The circle (*) shows a polypropylene tube containing pleural fluid isolated from another irradiated C57BL/6 mouse.